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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEB All Species: 4.55
Human Site: T2111 Identified Species: 25
UniProt: P20929 Number Species: 4
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20929 NP_004534 6669 772940 T2111 K N Y E N T K T S Y H T P A D
Chimpanzee Pan troglodytes XP_515832 6669 772715 T2111 K N Y E N T K T S Y H T P A D
Rhesus Macaque Macaca mulatta XP_001084585 2830 328533
Dog Lupus familis XP_533356 5625 649785 R1367 I R A A K A S R D I A S E Y K
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663414 6286 723048 A2020 S E K L Y K L A N E Q A K K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 41.7 61 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 55.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 42.2 70.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 71 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 20 0 20 0 20 0 0 20 20 0 40 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 40 % D
% Glu: 0 20 0 40 0 0 0 0 0 20 0 0 20 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % I
% Lys: 40 0 20 0 20 20 40 0 0 0 0 0 20 20 40 % K
% Leu: 0 0 0 20 0 0 20 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 40 0 0 40 0 0 0 20 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % Q
% Arg: 0 20 0 0 0 0 0 20 0 0 0 0 0 0 0 % R
% Ser: 20 0 0 0 0 0 20 0 40 0 0 20 0 0 0 % S
% Thr: 0 0 0 0 0 40 0 40 0 0 0 40 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 40 0 20 0 0 0 0 40 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _